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发表于 2016-7-10 23:39:23
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Bird Flu Nightmare Comes True -- in the Lab
Ever since H5N1 avian influenza emerged in the late 1990s, infecting billions of birds around the world, flu scientists have warned of potential apocalypse. The disease isn't highly contagious to people, but kills 60 percent of those who contract it. Should H5N1 ever become as infectious as seasonal flu strains, civilization could be headed for a Contagion-style meltdown.
In December, a federal U.S. security panel announced that two teams of researchers, one in the Netherlands and the other in Wisconsin, had engineered just such a virus. By understanding how avian influenza could jump into humans, hoped the researchers, we could better prevent that from happening, and design drugs and vaccines in preparation for that terrible day.
Some scientists supported the work. Others considered it an abomination, either because terrorists could hypothetically use the research to manufacture their own killer bug, or -- less hypothetically -- because ultra-high-security laboratories designed to prevent diseases from escaping have sometimes failed to do so.
Though formal publication is expected in 2012, the details have already been shared with hundreds of scientists. For good or for ill, this research has the potential to be the most important scientific discovery of 2011, and perhaps much more.
Image: Transmission electron microscope image of two H5N1 virions. (Center for Biologic Counterterrorism and Emerging Diseases)
禽流感梦魇成真——所幸是在实验室中
自从H5N1禽流感在上世纪90年代末出现,已感染了全世界范围内数十亿的禽类,科学家早已警告这其中潜藏的巨大危机。禽流感对人的传染性并不高,但一旦感染,致死率却高达60%。如果H5N1具备季节性流感的传染性,那么人类文明将遭遇一场传染病大灾难。
12月,美国政府的一个安全小组宣布,有两组研究人员,分别位于荷兰与威斯康辛,他们在实验室里制造出了这种具备高传染性的禽流感病毒。科学家试图通过理解禽流感病毒如何能够感染人类,令我们可以更好地阻止它发生,并设计药物与疫苗来为那可怕的一天做好准备。
尽管一些科学家支持这项工作,而另一些人则认为这很可怕,因为如果这项研究成果被恐怖分子掌握,后果将不堪设想,即便这很难发生,却还有另一种可能:实验室虽然具有高度的保护措施防止病毒外泄,但有时却难免意外。
尽管正式的报告将于2012年公布,但数百位科学家已经掌握了相关细节。无论这是件好事还是坏事,这项研究都可能是2011年最重要的科学发现。
图片:两个H5N1病毒的电子显微镜照片。(Centerfor Biologic Counterterrorism and Emerging Diseases)
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