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发表于 2018-5-12 10:12:44 | 显示全部楼层 |阅读模式
  Just ask any one of the 300,000 Americans who develop kidney stones: What
if the excruciating pain of passing one of those little devils could be
prevented by strapping yourself into a make-believe runaway mine train, throwing
your hands in the air and enduring G-forces as high as 2.5 for about three
minutes? Would you do it?
          Hell yeah, they’d do it.
          In a bit of medical research inspired by strange and remarkable patient
accounts, a Michigan State University urologist reports that, yes, riding a
medium-intensity roller coaster such as the Disney theme parks’ Big Thunder
Mountain Railroad can result in the painless passing of small, and even a few
large, kidney stones.
          For best results, ride in the back, where — roller coaster afficionados all
seem to agree — the thrills are greatest. Independent of kidney stone volume and
location, findings reported Sunday in the Journal of the American Osteopathic
Assn. showed that sitting in the back of the roller coaster resulted in an
average passage rate of 63.89%.
          Front-seat rides resulted in a far more modest passage rate of 16.67%.
          In what magical kingdom, you may well ask, does someone think to conduct
such research?
          Dr. David D. Wartinger, a professor emeritus at Michigan State University’s
College of Osteopathic Medicine, initiated the study after a series of patients
reported something almost too strange to believe: In the wake of riding Big
Thunder at Walt Disney World in Orlando, Fla., these patients said their kidney
stones passed painlessly from the kidney through the narrow duct of the ureter
and into the bladder. In one case, a patient told Wartinger that he passed one
kidney stone after each of three consecutive rides on the roller coaster.
          Using a 3-D printed model of that patient’s kidney, Wartinger and his
colleagues implanted three kidney stones of various sizes into the upper, middle
or lower passageways of the clear silicone model. Two of those mineral clusters,
which can form as the kidney filters waste from the bloodstream, were
small-to-moderate size — 4.5 millmeters and 13.5 mm. Those might pass through
the duct leading to the bladder without incident but could also cause
considerable pain and discomfort as they passed unaided. But a third measured
64.6 mm, a size that would rarely pass without treatment — the administration of
ultrasound shock waves, called lithotripsy, designed to break up the deposit and
allow it to pass.
          The researchers received permission from Walt Disney World first, then
concealed the kidney model in a backpack and rode Big Thunder 20 times, varying
their seat position between front and back.
          After analyzing the location of those three kidney stones at the end of
each ride, the researchers concluded that “findings support the anecdotal
evidence that a ride on a moderate-intensity roller coaster could benefit some
patients with small kidney stones,” Wartinger said. When the kidney stone was
large, the initial position of the kidney stone affected the likelihood of its
passing during the ride. But even those passed two in three times while the
silicone model rode the thrill ride.
          “Many people in the United States probably live within a few hours’ drive
of an amusement park containing a roller coaster with features capable of
dislodging calyceal renal calculi,” wrote Wartinger and co-author Dr. Marc A.
Mitchell of the Doctor’s Clinic in Poulsbo, Wash.
          Roller coaster therapy might be a good preventive treatment for people who
are high risk of developing obstructive kidney stones, wrote Wartinger and
Mitchell. They suggested that patients who have had kidney stones in the past,
or women who have had kidney stones and are thinking of becoming pregnant,
consider a thrill ride or two in a bid to clear tiny stones before the deposits
grow larger. Kidney stone sufferers who have had their deposits broken up by
lithotripsy might also consider a roller-coaster ride to finish the job, they

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