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狗狗成了小白鼠,失明治疗有新招(2/2)

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发表于 2016-8-2 10:59:32 | 显示全部楼层 |阅读模式
概述:威廉•贝尔春发表在美国国家科学院院刊的论文中论述了基因疗法对治疗色素性视网膜炎的可行性依据。
Hints:
Canine RP  
Beltran
University of Pennsylvania
ophthalmologist
William Beltran
Proceedings of the National Academy of Sciences
文中有四个连字符,请小心复查^_^
校对:听力小超人
翻译:shellyray163
组长:听力小超人
答疑:jackmgheartCanine RP is like the human variety which makes dogs a good model for studying the disease and possible treatments.
Beltran says the gene therapy appears to be safe and effective in stopping the progression of the disease, but he cautions that it can't do much to reverse vision loss. It can't restore the light-sensitive cells that have died and it can't grow new ones.
Beltran says tests in humans are still an estimated four-to-five years off. He wants to do more animal testing to see, for example, if the gene therapy has a long-lasting effect.
"And the reason for doing so is that the likelihood is when we get to treat patients, we will be treating individuals that are at a rather later stage of degeneration."
"The paper by University of Pennsylvania veterinary ophthalmologist William Beltran and colleagues is published in the Proceedings of the National Academy of Sciences."狗狗的色素性视网膜炎症状和人类的一样复杂多变,这使得狗狗们成为研究这项疾病以及可能的治疗方法的一个极好的典型研究对象。
贝尔春说基因疗法在阻止这种疾病的继续恶化方面显示出了它的安全性和有效性。但是他提醒到,这种疗法做太多的话对于阻止视力下降起不到根本性的作用。那样既不能修复已死的感光细胞,也生长不出新的感光细胞。
贝尔春说基因疗法的人体测试估计仍然需要四到五年的时间。他想要做更多的动物实验来看看,比如说,来看看基因疗法是否有持久的效果。
“这么做是因为,可能当我们开始治疗病人时,我们面对的这个病人可能将会处于一个更加恶化的病变阶段。”
“宾夕法尼亚大学的兽医眼科医师威廉•贝尔春和他的同事们在美国国家科学院院刊上发表了这篇论文。”
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