母乳喂养防艾滋(2/2)
概述:科学家们最近发现母乳中有一种蛋白质可以防止新生儿感染艾滋病病毒。Hints:
Sallie Permar
Tenacin-C
TNC
HIV
Proceedings of the National Academy of Sciences
校对:熔雪gemini
翻译&注解:kiwiangle
组长:mly123sm
答疑:vincit
发音点评:Persist1992
本期材料发音模仿地址:http://bulo.hujiang.com/menu/11885/item/847197/http://t1.g.hjfile.cn/listen/201311/20131118092109118269.mp3The low rate ofinfection was of great interest to researchers, including Sallie Permar. She led an effort to identify a substance in breast milk that may protect babies from infection.
Her team directed its attention to a protein called Tenacin-C, also called TNC. It is known to be involved in the process of healing wounds. But what purpose it serves in breast milk is not known.
The researchers exposed the TNC protein from breast milk of uninfected women to HIV. The protein linked up to the virus and made it harmless.
Anti-retroviral drugs remain effective in limiting the passing of HIV from mother to baby. But Professor Permar and her team suggest that TNC could be used in places where costly drug treatments are often not available.
She suggests that TNC could be given to babies before breastfeeding to provide additional protection against HIV. She adds that the protein is safe, because it is already a natural part of human milk. This may avoid the problem of HIV becoming resistant to anti-retroviral drugs.
The team reported its findings in the journal Proceedings of the National Academy of Sciences.(母乳喂养婴儿的)低感染率极大地吸引了包括萨利·朴玛在内的研究者。萨利·朴玛领导了一项研究,以识别母乳中保护婴儿免受感染的物质。
她的团队注意到了一种名叫Tenacin-C,又名TNC的蛋白质。现已知晓这种蛋白质有助于伤口愈合,但其在母乳中所起的作用尚不可知。
研究者使未感染妇女乳汁中提取的TNC蛋白质和HIV病毒相接触,TNC蛋白质和HIV病毒连接在了一起并使病毒变得无害了。
抗逆转录药物在限制HIV病毒从母体传染给婴儿方面仍十分有效。但是朴玛教授和她的团队表示TNC可以被用于无法获得昂贵药物治疗的情况。
她表示TNC可以在母乳喂养之前喂给婴儿,从而提供抵抗HIV病毒的额外保护。她补充说这种蛋白质很安全,因为它本来就存在于母乳之中。这就可以避免HIV病毒对抗逆转录药物产生抗药性的问题。
该团队在期刊《美国国家科学院院刊》上发表了这一发现。
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